The U.S. Food and Drug Administration today announced the approval of the vaccine Gardasil for the prevention of vaginal and vulvar cancer caused by Human Papillomavirus (HPV) types 16 and 18 in girls and women ages 9 to 26. These two HPV types cause 70 percent of cervical cancers, and are known to also cause some vulvar and vaginal cancers, but the percentages are not well defined.

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Fewer major bleeding complications with bivalirudin accounted for the drug’s observed significant clinical advantage over conventional heparin plus a glycoprotein IIb/IIIa inhibitor, according to its investigators.
Heartwire

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Women with unipolar major depression are more likely than men to achieve remission during treatment with the selective serotonin reuptake inhibitor (SSRI) citalopram, according to findings from the STAR*D (Sequenced Treatment Alternatives to Relieve Depression) study.
Reuters Health Information

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A new study suggests that even patients requiring aggressive blood pressure lowering after acute ischemic stroke should not be excluded from receiving tissue plasminogen activator therapy.
Medscape Medical News

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In a large, multisite study, medically trained clinicians with minimal specialty training in the treatment of alcohol dependence effectively delivered medical management intervention.
Medscape Medical News

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Updated letter on this current drug shortage

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Dr. Brown discusses the lack of regard in which physicians seem to be held these days.

Medscape Family Medicine

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In this video blog Ron Shapiro, MD discusses new clinical trial data on alemtuzumab and tacrolimus monotherapy after renal transplantation.

Medscape Transplantation

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The U.S. Food and Drug Administration today announced that it has approved an immune globulin product called Gamunex for the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP), a rare autoimmune disorder characterized by progressive weakness and impaired sensory function in the legs and arms.

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For patients with radiation or chemical cystitis refractory to standard therapy, submucosal injection of botulinum toxin A (BoNT-A) into the bladder wall appears promising, according to a case series reported in the September issue of BJU International.
Reuters Health Information

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